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עמוד הבית / אביטול ® 100 מ"ג / מידע מעלון לרופא

אביטול ® 100 מ"ג EVITOL ® 100 MG (TOCOPHEROL (VIT E) (AS TOCOPHERYL ACETATE))

תרופה במרשם תרופה בסל נרקוטיקה ציטוטוקסיקה

צורת מתן:

פומי : PER OS

צורת מינון:

טבליה : TABLETS

Special Warning : אזהרת שימוש

Warnings
Use in Pregnancy
There is no evidence of the safety of high doses of vitamin E in pregnancy, nor is there evidence from animal work that it is free from hazard. Therefore, do not use this drug in pregnancy, particularly in the first trimester.

Use in Lactation
No information is available on the excretion of vitamin E in breast milk. Therefore, it is recommended not to administer this drug to nursing mothers.

Adverse Reactions
Diarrhea and abdominal pain may occur with doses greater than 1 g/day.

Large doses {greater than 300 IU (135 mg potency)/day} have rarely caused intestinal cramps, fatigue, weakness, headache, blurred vision, rash, gonadal dysfunction, creatinuria, increased serum creatine kinase, increased serum cholesterol and triglycerides, increased urinary estrogens and androgens, and decreased serum thyroxine and triiodothyronine. These effects disappear after discontinuing the vitamin.

Precautions
Vitamin E has been reported to increase the risk of thrombosis in patients who are predisposed to this condition, including patients taking estrogens (see also Drug Interactions). This finding has not been confirmed but should be borne in mind when selecting patients for treatment, in particular women taking oral contraceptives containing oestrogen.

A higher incidence of necrotising enterocolitis has been noted in lower weight premature infants (less than 1.5kg) treated with vitamin E.

Effects on Driving

                
שימוש לפי פנקס קופ''ח כללית 1994 Vitamin E deficiency, hemolytic anemia and retrolental fibroplasia in premature infants, intermittent claudication, idiopathic nocturnal leg cramps, adjuvant in vitamin A therapy in arteriosclerotic chorioretinopathy and in various forms of deafness, adjunct to specific hormonal therapy in male infertility
תאריך הכללה מקורי בסל 01/01/1995
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לתרופה במאגר משרד הבריאות

אביטול ® 100 מ"ג

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