Posology : מינונים

4.2. Posology and Method of Administration

Posology
Adults, the elderly and children:
The dosage depends on the age, weight, clinical and biological (acid-base balance) conditions of the patient, and concomitant therapy.

Recommended dosage:
The amount of Ringer Lactate solution Fresenius needed to restore normal blood volume is 3 to 5 times the volume of lost blood.
The recommended dosage is:
- for adults: 500 ml to 3 L/24h
- for babies and children: 20 ml to 100 ml/kg/24 h

Administration rate:
The infusion rate is usually 40 ml/kg/24h in adults.
In pediatric patients the infusion rate is 5 ml/kg/h on average but the value varies with age: 6-8 ml/kg/h for infants, 4-6 ml/kg/h for toddlers, and 2-4 ml/kg/h for schoolchildren. In children with burns, the dose is on average 3.4 ml/kg/percent burn at 24 h post-burn and 6.3 ml/kg/percent burn at 48 h. In severely head-injured children the dose is on average 2850 ml/m².
Infusion rate and total volume can be higher in surgery or in case of need.

Note:
- infants and toddlers: age ranges from about 28 days to 23 months (a toddler is an infant who can walk)
- children and schoolchildren: age ranges from about 2 years to 11 years.

Administration:
The administration is performed by intravenous route using sterile and non-pyrogenic equipment.