Interactions : אינטראקציות

4.5. Interaction with other medicinal products and other forms of interaction
No interaction studies have been performed

Ceftriaxone must not be administered simultaneously with intravenous calcium-containing solutions, including Oliclinomel, through the same infusion line because of the risk of precipitation of ceftriaxone- calcium salt.

If the same infusion line is used for sequential administration, the line must be thoroughly flushed between infusions with a compatible fluid (e.g. physiological salt solution) to avoid precipitation Oliclinomel contains vitamin K, naturally present in lipid emulsions. The amounts of Vitamin K in recommended doses of Oliclinomel, are not expected to influence effects of coumarin derivatives.
This emulsion for infusion must not be administered simultaneously with blood through the same infusion tubing because of the possibility of pseudoagglutination.
The lipids contained in this emulsion may interfere with the results of certain laboratory tests (for example, bilirubin, lactate dehydrogenase, oxygen saturation, blood haemoglobin) if the blood sample is taken before the lipids have been eliminated (these are generally eliminated after a period of 5 to 6 hours without receiving lipids).
Due to the potassium content of Oliclinomel, special care should be taken in patients treated with potassium- sparing diuretics (e.g, amiloride, spironolactone, triamterene) angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor antagonists or the immunosuppressants tacrolimus and cyclosporine in view of the risk of hyperkalemia.