Posology : מינונים

4.2    Posology and method of administration

Continuous renal replacement therapy including the prescription of this medicinal product should be performed under the direction of a physician with experience in these treatments.

Posology
In acute kidney injury, a continuous treatment with a dose of 2000 ml/h MULTIBIC potassium-free/2/3/4 mmol/l potassium is appropriate in adults with a body weight of 70 kg to remove metabolic waste products depending on the metabolic status of the patient. The dose should be adapted to the body size of the patient.

In patients with chronic kidney disease, unless clinically indicated otherwise, the dose of MULTIBIC potassium-free/2/3/4 mmol/l potassium should be at least one third of the body weight per session with three sessions applied per week. Increasing the volume applied per week or distributing this weekly volume to more than 3 treatments per week can be required.

The dose and the duration of haemodialysis, haemofiltration or haemodiafiltration necessary in treatment of acute states of intoxication depends on the toxin and its concentration and the severity of clinical symptoms and has to be clinically decided on the individual patient’s condition.

A maximum dose of 75 litre per day is recommended.

Paediatric population
The safety and efficacy of MULTIBIC potassium-free/2/3/4 mmol/l potassium in children have not yet been established (see sections 4.4 and 5.1).

Method of administration
For intravenous use and haemodialysis.
For instructions on use of the product, see section 6.6.