Pharmacological properties : תכונות פרמקולוגיות

Pharmacodynamic Properties

5.1   Pharmacodynamic properties

Pharmacotherapeutic group: Iron-containing preparations,
ATC code: B03AC.

In the event of iron loss or increased iron requirements in the organism, the iron content in Ferrlecit substitutes the lack of iron. Thus, a sufficient quantity of iron can be provided to the erythropoietic centres for haemoglobin formation. The formation of physiological iron reserves is also possible.

The efficacy of iron replacement is initially expressed by an increase in the reticulocyte count as well as an increase in the haemoglobin value, the haemoglobin concentration/single erythrocyte count and an increase in the red blood cell count.

Pharmacokinetic Properties

5.2   Pharmacokinetic properties

Sodium ferric gluconate complex enters the liver via the blood. There, after enzymatic splitting and release of the iron, the trivalent iron binds to transferrin, the carrier protein for plasma iron, which takes over the transport to the erythropoiesis centres and the depots. If no pathological iron loss occurs due to bleeding, the iron content of the organism is  almost completely preserved,  apart from minimal physiological daily iron elimination.