Posology : מינונים

4.2 Posology and method of administration
500mg XL ‐ one tablet once or twice daily
The total daily dose of Etopan XL should not exceed 1,200mg.

As with other NSAIDs, the lowest dose and longest interval should be sought for each patient. Therefore, after observing the response to initial therapy with Etopan XL, the dose and frequency should be adjusted to suit individual patient’s needs (tolerance and response). In responsive patients, partial symptomatic relief of symptoms usually occurs within 1 or 2 weeks, although maximum effectiveness may occur only after several weeks of therapy.
During long‐term administration the dose of Etopan XL may be adjusted, up or down, depending on the patient’s clinical response (maximum dose 1200 mg/day).
As with other NSAIDs, Etopan XL is preferably taken after meals or with food or antacids to reduce gastrointestinal irritation, especially during chronic use.
However, for faster absorption when a rapid initial effect is required, the first 1 or 2 doses may be taken 30 minutes before meals or at least 2 hours after meals. If an antacid is taken concurrently, an aluminum and magnesium‐ containing formulation may be preferred. It is recommended to take Etopan XL tablets with a full glass of water and that the patient remains in an upright position for 15‐30 minutes after administration. Patients should be advised to avoid alcoholic beverages while under treatment with this medicine.