Posology : מינונים

4.2 Posology and method of administration

Posology
The dosage of Budicort Turbuhaler is individual.

Budicort Turbuhaler is for oral inhalation
When transferring patients to Turbuhaler from other devices, treatment should be individualised, The drug and method of delivery should be considered.

The dosage should be individualised.
The dose should always be reduced to the minimum needed to maintain good asthma control.
Adults (including elderly) and children over 12 years of age: When starting treatment, during periods of severe asthma and while reducing or discontinuing oral glucocorticosteroids, the dosage in adults should be 200 - 1600 micrograms daily, divided into 2-4 administrations.
In less severe cases and children over 12 years of age, 200 - 800 micrograms daily, in divided doses, may be used. During periods of severe asthma, the daily dosage can be increased to up to 1600 micrograms, in 2-4 divided doses.

Children 6 years-12 years of age: 200 - 800 micrograms daily, in divided doses. During periods of severe asthma, the daily dose can be increased up to 800 micrograms.

The maintenance dose should be the lowest possible.
It is possible that the patient will not taste or perceive any medicine when Budicort Turbuhaler is used; this is because such a small amount of substance is dispensed.


In patients where an increased therapeutic effect is desired, an increased dose of Budicort is recommended because of the lower risk of systemic effects as compared with a combined treatment with oral glucocorticosteroids.
Patients dependant on oral glucocorticosteroids


Budicort Turbuhaler may permit replacement or significant reduction in dosage of oral glucocorticosteroids while maintaining asthma control. For further information on the withdrawal of oral corticosteroids, see section 4.4.



Patients should be reminded of the importance of taking prophylactic therapy regularly, even when they are asymptomatic. A short-acting inhaled bronchodilator should be made available for the relief of acute asthma symptoms.

There is no experience of treatment of patients with impaired hepatic or renal function. Since budesonide is predominantly eliminated through hepatic metabolism, increased exposure may be expected in patients with severe cirrhosis of the liver.


Instructions for correct use of Budicort Turbuhaler:
It is important that the inhaler is used correctly. A detailed description of how the Turbuhaler is used is supplied with every pack.


Instructions for the correct use of Budicort Turbuhaler

Turbuhaler is inspiratory flow-driven which means that, when the patient inhales through the mouthpiece, the substance will follow the inspired air into the airways.

Note: It is important to instruct the patient:

• To carefully read the instructions for use in the patient information leaflet, which is packed with each Turbuhaler
• To breathe in forcefully and deeply through the mouthpiece to ensure that an optimal dose is delivered to the lungs
• Never to breathe out through the mouthpiece
• To rinse the mouth out with water and spit it out, or to brush the teeth after inhaling the prescribed dose, to minimise the risk of oropharyngeal thrush

The patient may not taste or feel any medication when using Turbuhaler due to the small amount of drug dispensed.