Pharmaceutical particulars : מידע רוקחי

6 PHARMACEUTICAL PARTICULARS
6.1 LIST OF EXCIPIENTS
AVAMYS Nasal Spray also contains the following excipients: Glucose Anhydrous, Dispersible Cellulose, Benzalkonium Chloride solution, Polysorbate 80, Disodium Edetate, and Purified Water.

6.2 INCOMPATIBILITIES

Incompatibilities were either not assessed or not identified as part of the registration of this medicine.

6.3   Shelf life

The expiry date of the product is indicated on the label and packaging materials.
In-use shelf life: 2 months.
6.4   Special precautions for storage

Do not refrigerate or freeze.

6.5   Nature and contents of container
Avamys is a white suspension contained in an amber glass bottle fitted with a metering atomizing spray pump. This bottle is incorporated within a predominantly off-white plastic device with a dose indicator window, a light blue side-actuated lever and a lid which contains a stopper.
The medicinal product is available in three pack sizes: 1 bottle of 30, 60 or 120 sprays.
Not all pack sizes may be marketed.

6.6 PHYSICOCHEMICAL PROPERTIES

Description
Fluticasone furoate is practically insoluble or insoluble in water, and slightly soluble in acetone, dimethylsulphoxide and ethanol.

Chemical structure



CAS number
397864-44-7
Chemical Name:
Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-17-[(2 furanylcarbonyl)oxy]-11- hydroxy-16-methyl-3-oxo-, S-
(fluoromethyl) ester, (6α,11β,16α,17α)- (9CI)

Molecular Formula: C27H29F3O6S