Adverse reactions : תופעות לוואי

4.8   Undesirable effects

The following frequency categories are used for the evaluation of undesirable effects: 
Very common           (≥1/10)
Common                (≥1/100 to <1/10)
Uncommon              (≥1/1,000 to <1/100)
Rare                  (≥1/10,000 to <1/1,000)
Very rare             (<1/10,000)
Not known             (frequency cannot be estimated from the available data) 
Skin and subcutaneous tissue disorders
There may be rare cases of reduced pigmentation of the skin, as well as skin irritation in the form of reddening, burning, drying out and desquamation. In very rare cases the above symptoms may also be an expression of a hypersensitivity reaction (allergic contact eczema).
At the beginning of treatment the acne may appear to worsen, with an increase in the number of inflammatory symptoms; this is a sign that the medicine is beginning to act and is mostly of a temporary nature. Treatment with Aknemycin Plus should therefore not be discontinued.
However, the frequency of application can be reduced temporarily.

Not known: acute generalised exanthematous pusulosis (AGEP)

Reporting of side effects
Side effects can be reported to the Ministry of Health by clicking on the link “Report Side Effects of Drug Treatment” that appears on the homepage of the Ministry of Health’s website (www.health.gov.il) which links to an online form for reporting side effects, or by the following link: https://sideeffects.health.gov.il/
In addition, you can report by emailing the Registration Holder's Patient Safety Unit at: drugsafety@neopharmgroup.com