Posology : מינונים

4.2 Posology and method of administration
15 mg (one tablet of Spasmex 15 or half a tablet of Spasmex 30) should be taken three times a day, or 30 mg in the morning (two tablets of Spasmex 15 or one tablet of Spasmex 30) and 15 mg in the evening.


Patients with reduced kidney function
In patients with severely impaired renal function (Creatinine clearance between 10 and 30 ml/ min/ 1.73 m2) a daily dose of 15 mg should not be exceeded.

Patients with reduced liver function
Dose adjustment does not appear necessary in patients with a mild to moderate impairment in liver function (Child-Pugh 5-6 or 7-9) (see section 5.2 Pharmacokinetic properties).
Studies for patients with severe liver dysfunction (Child-Pugh > 10; class C) have not been carried out meaning that treatment cannot be recommended in these cases.


Use in children
Treatment in children under 12 years old is not recommended as no data exist.

Mode and duration of treatment
The film-coated tablets should be swallowed whole with a sufficient quantity of liquid before a meal on an empty stomach. The necessity of a continuation of treatment should be monitored at regular intervals of 3 – 6 months.