Posology : מינונים

4.2   Posology and method of administration
Posology
Adults and adolescents (12 years and older)
The usual recommended dose is two actuations in each nostril twice daily (morning and evening).
Children below 12 years
Ryaltris is not recommended for use in children below 12 years of age as safety and efficacy has not been established in this age group.


Elderly
No dose adjustment is required in this population.
Renal and hepatic impairment
There are no data in patients with renal and hepatic impairment, however no dose adjustment is expected to be required in these populations considering the absorption, metabolism and elimination of the active substances (see section 5.2).


Method of administration
Ryaltris is for nasal use only.
Prior to administration of the first dose, shake container well and actuate the pump 6 times (until a uniform spray is obtained). If the pump is not used for 14 days or longer, re-prime the pump with 2 actuations until a uniform spray is observed, before next use.
Shake container for minimum 10 seconds before each use. After using the spray, wipe the nozzle carefully with a clean handkerchief or tissue and replace the cap, to avoid that the nozzle gets blocked. The bottle should be discarded after the labelled number of actuations or within 2 months of first use.