Contraindications : התוויות נגד

4.3 Contraindications

Hypersensitivity to the active substances Dexamethasone Sodium Phosphate and/or Neomycin Sulphate and/or Polymyxin B Sulphate, or to any of the excipients listed in section 6.1.

The use of Desoren Ear Drops is contra-indicated in patients in whom perforation of the tympanic membrane is known or suspected.

Due to the known ototoxic and nephrotoxic potential of neomycin sulphate, the use of Desoren Ear Drops in large quantities or on large areas for prolonged periods of time is not recommended in circumstances where significant systemic absorption may occur.

The use of Desoren Ear Drops is contra-indicated in patients who have demonstrated allergic hypersensitivity to cross-sensitising substances such as framycetin, kanamycin, gentamicin and other related aminoglycoside antibiotics.
The use of Desoren Ear Drops is contra-indicated in the presence of untreated viral, fungal and tubercular infections.

A possibility of increased absorption exists in very young children, thus Desoren Ear Drops shall not be used in neonates and infants (up to 3years). In neonates and infants, absorption by immature skin may be enhanced and renal function may be immature.