Pharmacological properties : תכונות פרמקולוגיות

Pharmacodynamic Properties

5.1   Pharmacodynamic properties

Pharmacotherapeutic group: herbal medicinal product for respiratory cold diseases ATC-Code: R05CA
The results from in-vitro studies and animal studies with preparations from thyme herb and thyme oil or its main component thymol suggest weak expectorating and spasmolytic effects.

The expectorating effects of thyme herb are probably due to a stimulation of the bronchial ciliated epithelium that is triggered by a reflectory stimulation of the Nervus vagus via the gastric mucosal membrane and resorption as a result of pulmonal secretion via a direct stimulation of serous glandular cells.

The expectorating effects of ivy leaves are probably due to a stimulation of the gastric mucous membrane that is triggered by a reflectory stimulation of sensory fibers of the parasympathetic nervous system in the bronchial mucous membrane.

There are no data available on the pharmacological effects in humans neither for individual components nor the fixed combination.

Pharmacokinetic Properties

5.2   Pharmacokinetic properties

There are no data available on pharmacokinetics and bioavailability with preparations from thyme herb and ivy leaves.