Posology : מינונים

2       DOSAGE AND ADMINISTRATION

2.1 Dosage and Schedule
Children/Adolescents (12 months through 18 years of age): Vaccination consists of a primary 0.5-mL dose administered intramuscularly, and a 0.5-mL booster dose administered intramuscularly 6 to 18 months later.

Adults (≥19 years of age): Vaccination consists of a primary 1.0-mL dose administered intramuscularly, and a 1.0-mL booster dose administered intramuscularly 6 to 18 months later.

Interchangeability of the Booster Dose: A booster dose of VAQTA may be given at 6 to 12 months following the primary dose of another inactivated hepatitis A vaccine (i.e., HAVRIX) [see Clinical Studies (14.6)].

2.2     Method of Administration
For intramuscular use only.
•     Shake well to obtain a slightly opaque, white suspension before withdrawal and use.
•     Thoroughly agitate to maintain suspension of the vaccine.
•     Discard if the suspension does not appear homogenous or if extraneous particulate matter remains or discoloration is observed.

For adults, adolescents, and children older than 2 years of age, the deltoid muscle is the preferred site for intramuscular injection. For children 12 through 23 months of age, the anterolateral area of the thigh is the preferred site for intramuscular injection.

Single-Dose Vial Use
•     Withdraw dose of vaccine from the single-dose vial using a sterile needle and syringe.