Pharmaceutical particulars : מידע רוקחי

6.     Pharmaceutical particulars
6.1    List of excipients
Disodium edetate, sodium hydroxide, water for injections.

6.2      Incompatibilities
In vitro, mesna is incompatible with carboplatin, cisplatin and nitrogen mustard.
However, concomitant administration is possible if this is carried out via separate accesses.
These medicines do not affect each other in the body.

6.3   Shelf life
The expiry date of the product is indicated on the packaging materials.
Mesna-Cell can be diluted with 5% glucose solution or 0.9% sodium chloride solution.
From a microbiological point of view, the ready-to-use preparation should be used immediately. If the ready-to-use preparation is not used immediately, in-use storage times and conditions prior to use are the responsibility of the user and would normally not be longer than 24 hours at 2°C to 8°C, unless dilution has taken place under controlled and validated aseptic conditions.

6.4    Special precautions for storage
MESNA-cell® 100 mg/ml: 400 mg
Store below 30°C.

MESNA-cell® 100 mg/ml: 1,000 mg
MESNA-cell® 100 mg/ml: 5,000 mg
Store below 25°C.
6.5   Nature and contents of container
MESNA-cell® 100 mg/ml: 400 mg
10 ampoules

MESNA-cell® 100 mg/ml: 1,000 mg
1 or 5 vials
MESNA-cell® 100 mg/ml: 5,000 mg
1 vial

6.6  Instructions for use and handling
MESNA-cell® is for single use only. Discard appropriately any contents remaining after first use.

Any unused medicinal product or waste material should be disposed in accordance with local requirements.