Adverse reactions : תופעות לוואי

4.8 Undesirable effects
The following convention has been utilised for the classification of the frequency of adverse reactions: very common (>1/10), common (>1/100 to <1/10), uncommon (>1/1000 to <1/100), rare (>1/10,000 to <1/1000) and very rare (<1/10,000), not known (cannot be estimated from available data).
Adverse reactions identified during post-marketing use with chlorphenamine are listed below.
As these reactions are reported voluntarily from a population of uncertain size, the frequency of some reactions is unknown but likely to be rare or very rare: 
System Organ Class                    Adverse Reaction            Frequency Sedation, somnolence        Very common
Nervous system                        Disturbance in attention,   Common disorders*                            abnormal coordination,
dizziness headache
Eye disorders                         Blurred Vision              Common Nausea, dry mouth           Common
Ahiston-2mg-tablets-LC+KL-Notification-SPC-12-2021
Gastrointestinal disorders            Vomiting, abdominal           Unknown pain, diarrhoea, dyspepsia
Immune system disorders:              Allergic reaction,            Unknown angioedema, anaphylactic reactions
Metabolism and                        Anorexia                      Unknown nutritional disorders
Blood and lymphatic                   Haemolytic anaemia,           Unknown system disorders                      blood dyscrasias
Musculoskeletal and                   Muscle twitching, muscle      Unknown connective tissue                     weakness disorders
Psychiatric disorders                 Confusion*, excitation*,      Unknown irritability*, nightmares*,
depression
Renal and urinary                     Urinary retention             Unknown disorders
Skin and subcutaneous                 Exfoliative dermatitis,       Unknown disorders                             rash, urticaria,
photosensitivity
Respiratory, thoracic and             Thickening of bronchial       Unknown mediastinal disorders                 secretions
Vascular disorders                    Hypotension                   Unknown Hepatobiliary disorders               Hepatitis, including          Unknown jaundice
Ear and labyrinth                     Tinnitus                      Unknown disorders
Cardiac disorders                     Palpitations, tachycardia,    Unknown arrythmias
General disorders and                 Fatigue                       Common administration site                   Chest tightness               Unknown conditions

* Children and the elderly are more likely to experience the neurological anticholinergic effects and paradoxical excitation (eg. increased energy, restlessness, nervousness).

Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product.
Any suspected adverse events should be reported to the Ministry of Health according to the National Regulation by using an online form https://sideeffects.health.gov.il/