Indications : התוויות

4.1 Therapeutic indications
Benzodiazepine antagonist for reversal of benzodiazepine anesthesia, as well as for patients with Benzodiazepine intoxication.
In a hospital setting:
In anaesthesiology to neutralise the sedative effects of benzodiazepines on the central nervous system in adults and children older than 1 year:
• reversal of sedative effect during general anaesthesia induced and maintained by benzodiazepines,
• reversal of conscious sedation induced by benzodiazepines in short operations with a diagnostic or therapeutic objective.

In intensive care to neutralise the sedative effects of benzodiazepines on the central nervous system and treat a coma of unknown aetiology, in adults and children (including newborns) if the semiology is compatible with the hypothesis of a benzodiazepine or related substance- induced coma:
• diagnosis and/or treatment of intentional or accidental benzodiazepine overdose, • aetiological diagnosis of an unexplained coma in order to differentiate what is caused by a benzodiazepine from another cause (pharmacological or neurological).
• specific cancellation of the effects on the central nervous system by excessive benzodiazepine doses (re-establishment of spontaneous ventilation to avoid intubation or interrupt ventilatory assistance).

In an emergency situation or medical transport, in adults and children older than 6 years:
• reversal of benzodiazepine-induced conscious sedation in case of respiratory depression or apnoea.