Posology : מינונים

4.2   Posology and method of administration

Posology
Adults, elderly patients, adolescents and children:
The dosage depends on the age, bodyweight, clinical and biological conditions of the patient and the concomitant therapy.

Recommended dosage
The recommended dosage is:
− Adolescents, adults and elderly patients:
500 mL - 3 L/24 hours, equivalent to 1 - 6 mmol sodium/kg BW/24 hours and 0.03 - 0.17 mmol potassium/kg BW/24 hours
− Infants and children:
20 mL - 100 mL/kg BW/24 hours, equivalent to 3 - 14 mmol sodium/kg BW/24 hours and 0.08 - 0.40 mmol potassium/kg BW/24 hours.

Infusion rate
The maximum infusion rate depends on the patient’s fluid and electrolyte requirements, bodyweight, clinical condition and biological status.
In paediatric patients, the infusion rate is 5 mL/kg BW/h on average, but the value varies with age: 6 - 8 mL/kg BW/h for infants, 4 - 6 mL/kg BW/h for toddlers, and 2 - 4 mL/kg BW/h for children.
Note:
− Infants and toddlers:      Age ranges from 28 days - 23 months (a toddler is an infant who can walk.)
− Children:                  Age ranges from 2 - 11 years

Paediatric population
The safety and efficacy of Sterofundin ISO in newborn infants (below the age of 28 days) has not been established.

Method and duration of administration
For intravenous use as infusion only.
Sterofundin ISO can be infused into peripheral veins (see section 3 for pH and theoretical osmolarity).
If administration is by rapid infusion under pressure, all air must be withdrawn from the plastic container and infusion set prior to infusion, as otherwise there is a risk of producing air embolism during infusion.
Controls:
Fluid balance, plasma electrolyte concentrations and blood pH must be monitored during administration.
Sterofundin ISO may be administered as long as there is an indication for fluid replacement.