Contraindications : התוויות נגד

4.3. Contraindications
The use of Dexamethasone Panpharma is contraindicated in patients                with hypersensitivity to any of its ingredients.

Anaphylactoid and hypersensitivity reactions have been reported following the injection of dexamethasone. These reactions, although they occur on rare occasions in patients with a history of allergy to any drug, are more common.

Corticosteroids may mask some signs of infection or even induce the appearance of new infections or worsen existing ones. Therefore, the use of Dexamethasone Panpharma is contraindicated, unless the patient receives suitable chemotherapy and is under strict medical supervision, in systemic fungal infections, disseminated tuberculoses, latent tuberculoses or with tuberculin reactivity, in patients with a known or suspected parasitic infection of the GI tract, herpes, measles and chickenpox.

Administration of live virus vaccines, including smallpox, is contraindicated in individuals receiving immunosuppressive doses of corticosteroids. If inactivated viral or bacterial vaccines are administered, corticosteroids can prevent the expected immunological response of the vaccination (increase in serum antibodies) from occurring. However, immunization procedures may be undertaken in patients receiving corticosteroids as replacement therapy, e.g., for Addison's disease.

Similarly, prolonged treatment with dexamethasone is not recommended in congestive heart disease, myasthenia gravis, peptic ulcer or oesophagitis, diabetes and ocular herpes simplex.

Idiopathic thrombocytopenic purpura in adult is contraindicated by the intramuscular route.