Posology : מינונים

4.2   Posology and method of administration
The concentration of the albumin preparation, dosage and infusion-rate must be adjusted to the patient’s individual requirements.

Posology
The dose required depends on the size of the patient, the severity of trauma or illness and on continuing fluid and protein losses. Measures of adequacy of circulating volume and not plasma albumin levels should be used to determine the dose required.

If human albumin is to be administered, haemodynamic performance should be monitored regularly. This may include:
- arterial blood pressure and pulse rate
- central venous pressure
- pulmonary artery wedge pressure
- urine output
- electrolyte
- haematocrit/haemoglobin.

Paediatric population
The safety and efficacy of UMAN ALBUMIN in children, including premature infants, have not been established by controlled clinical trials and its use in paediatric population is based only on estabilished medical practice. For this reason, UMAN ALBUMIN must be used in children and premature infants only if clearly necessary.

Patients with renal impairment
UMAN ALBUMIN can be administered to dialysis patients as the aluminium content of the finished product is not more than 200 g/l.

Method of administration
Human albumin can be directly administered by the intravenous route, or it can also be diluted in an isotonic solution (e.g. 5% glucose or 0.9% sodium chloride).
The infusion rate should be adjusted according to the individual circumstances and the indication.
In plasma exchange the infusion-rate should be adjusted to the rate of removal.