Posology : מינונים

4.2   Posology and method of administration
Posology
ChloraPrep may be used on all age groups and patient populations.

Paediatric population
However, ChloraPrep should be used with care in newborn babies, especially those born prematurely (see also section 4.4, Special warnings and precautions for use).

One applicator is used containing 1 ml, 1.5 ml, 3 ml, 10.5 ml or 26 ml of the ChloraPrep alcoholic solution.

Method of administration
For cutaneous use

The choice of applicator will depend on the invasive procedure being undertaken and the clinician’s preference.

Applicator         Coverage Area (cm x cm)                 For Procedures such as: 1 ml
- Routine venipuncture
- Blood culture collection
8 X 10               - Peripheral (arterial line) cannulation
- Simple biopsy

1.5 ml

-Routine venipuncture
- Blood culture collection
10 X 13               - Peripheral (arterial line) cannulation
1.5 ml (Frepp)                                        - Simple biopsy - Dialysis Fistula/Graft site cleansing


3 ml                                                  - Midline & Central Venous Catheter 15 X 15
(CVC) insertion and maintenance
- Peritoneal dialysis site cleansing


10.5 ml

- Minor and major surgical procedures
25 X 30               - Implantable device placement
- Prosthetic device placement or removal
- Midline, Peripheral Intravascular
Central Catheter (PICC) & CVC
26 ml                                                   insertion and maintenance
- Cardiac catheterisation and Cardiac
Cath Lab procedures
50 X 50
- Interventional Radiology procedure


The applicator is removed from the wrapper and held with the sponge facing downward. The applicator is squeezed gently to break the ampoule containing the antiseptic solution, which is released onto the sponge in a controlled flow (for the 26 ml applicator the lever is pressed).
Pinch wings once only to activate the applicator and release the antiseptic. Do not repeatedly pinch or pump the wings in an attempt to accelerate the saturation of the foam. The broken ampoule remains safely contained within the applicator. The sponge is gently pressed against the patient’s skin in order to apply the antiseptic solution. Once the solution is visible on the skin, use gentle back and forth strokes to prep the site for 30 seconds.
The 26 ml applicator includes two swabs. Clean intact umbilicus with enclosed swabs when applicable. (Moisten swabs by pressing against solution-soaked sponge applicator.) The area covered should be allowed to air dry completely

It is recommended that ChloraPrep remain on the skin post-procedure to provide continued antimicrobial activity. If removal is necessary, remove with soap and water or alcohol.