Contraindications : התוויות נגד

4 CONTRAINDICATIONS
Yasmin Plus contraindicated in females who are known to have or develop the following conditions: Renal impairment
Adrenal insufficiency
A high risk of arterial or venous thrombotic diseases. Examples include women who are known to: o Smoke, if over age 35 [see Boxed Warning and Warnings and Precautions (5.1)] o Have deep vein thrombosis or pulmonary embolism, now or in the past [see Warnings and Precautions (5.1)] o Have cerebrovascular disease [see Warnings and Precautions (5.1)] o Have coronary artery disease [see Warnings and Precautions (5.1)] o Have thrombogenic valvular or thrombogenic rhythm diseases of the heart (for example, subacute bacterial endocarditis with valvular disease, or atrial fibrillation) [see Warnings and Precautions (5.1)] o Have inherited or acquired hypercoagulopathies [see Warnings and Precautions (5.1)] o Have uncontrolled hypertension [see Warnings and Precautions (5.6)] o Have diabetes mellitus with vascular disease [see Warnings and Precautions (5.8)] o Have headaches with focal neurological symptoms or have migraine headaches with or without aura if over age 35 [see Warnings and Precautions (5.9)]
• Undiagnosed abnormal uterine bleeding [see Warnings and Precautions (5.10)] • Current diagnosis of, or history of, breast cancer which may be hormone-sensitive [see Warnings and Precautions (5.3)]
• Liver tumor (benign or malignant) or liver disease [see Warnings and Precautions (5.4) and Use in Specific Populations (8.7)]
• Use of Hepatitis C drug combinations containing ombitasvir/paritaprevir/ritonavir, with or without dasabuvir due to the potential for ALT elevations [see Warnings and Precautions (5.5) and Drug Interactions (7.3)].
Hypersensitivity to the active substance or to any of the excipients (inactive ingredients) listed in section 11.