Indications : התוויות

4.1. Therapeutic Indications

Doxycycline has been found clinically effective in the treatment of a variety of infections caused by susceptible strains of Gram-positive and Gram-negative bacteria and certain other microorganisms.
Respiratory tract infections: Pneumonia and other lower respiratory tract infections due to susceptible strains of Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis and other organisms. Mycoplasma pneumonia. Treatment of chronic bronchitis, sinusitis.
Urinary tract infections: Infections caused by susceptible strains of Klebsiella species, Enterobacter species, Escherichia coli, Streptococcus faecalis and other organisms.
Sexually transmitted diseases: Infections due to Chlamdyia trachomatis including uncomplicated urethral, endocervical or rectal infections. Non-gonococcal urethritis caused by Ureaplasma urealiticum (T- mycoplasma). Doxylin 100 is also indicated in infections due to Calymmatobacterium granulomatis. Doxylin is an alternative drug in the treatment of gonorrhoea and syphilis.
Since Doxycycline is a member of the tetracycline series of antibiotics, it may be expected to be useful in the treatment of infections which respond to other tetracyclines, such as: Ophthalmic infections: Treatment of trachoma, although the infectious agent is not always eliminated, as judged by immunofluorescence. Inclusion conjunctivitis may be treated with oral Doxycycline alone or in combination with topical agents.
Rickettsial infections: Rocky Mountain spotted fever, typhus group, Q fever, Coxiella endocarditis.
Other infections: Psittocosis, brucellosis (in combination with streptomycin), cholera, bubonic plague, louse and tick-borne relapsing fever including stage 1 and stage 2 Lyme disease, leptospirosis, tularaemia glanders, chloroquine-resistant falciparum malaria and acute intestinal amoebiasis (as an adjunct to amoebicides).
Infections due to susceptible strains of Bacteroides species and Listeria species.

Doxylin is an alternative drug in the treatment of leptospirosis, gas gangrene and tetanus.
Doxylin is indicated for prophylaxis in the following conditions: Scrub typhus, traveller's diarrhoea (enterotoxigenic Escherichia coli), leptospirosis, malaria and cholera.
Anthrax due to Bacillus anthracis, including inhalational anthrax (post exposure): to reduce the incidence or progression of disease following exposure to aerosolized Bacillus anthracis.