Posology : מינונים

4.2 Posology and method of administration
The initiation of Copaxone treatment should be supervised by a neurologist or a physician experienced in the treatment of MS.
Posology
The recommended dosage in adults is 40 mg of Copaxone (one pre-filled syringe/ one pre-filled pen), administered as a subcutaneous injection three times a week with at least 48 hours apart.
At the present time, it is not known for how long the patient should be treated.


A decision concerning long term treatment should be made on an individual basis by the treating physician.


Paediatric population
The safety and effectiveness of Copaxone have not been established in individuals below 18 years of age

Elderly
Copaxone has not been specifically studied in the elderly.

Patients with renal impairment
Copaxone has not been specifically studied in patients with renal impairment (see section 4.4).

Method of administration
Copaxone is for subcutaneous use.
Patients should be instructed in self-injection techniques and should be supervised by a health-care professional the first time they self-inject and for 30 minutes after.
A different site should be chosen for every injection, so this will reduce the chances of any irritation or pain at the site of the injection. Sites for self-injection include the abdomen, arms, hips, and thighs.


The CSYNC device is a multiple use autoinjector that can be used with Copaxone pre-filled syringes and it has not been tested with other pre-filled syringes. The CSYNC device should be used as recommended in the information provided by the device manufacturer.