Posology : מינונים

4.2        Posology and method of administration
Posology

Daily dose:
1 ml up to max. 2 ml Omegaven/kg body weight
= 0.1 g up to max. 0.2 g fish oil/kg body weight
= 70 ml up to max. 140 ml Omegaven for a patient with a body weight of 70 kg.
Maximum infusion rate:
The infusion rate should not exceed 0.5 ml Omegaven/kg body weight/hour corresponding to 0.05 g fish oil/kg body weight/hour.

The maximum infusion rate should be strictly adhered to, otherwise a severe increase in the serum triglyceride concentration can be observed.
Omegaven should be administered simultaneously with other fat emulsions. On the basis of a recommended total daily lipid intake of 1 - 2 g/kg body weight, the fish oil portion from Omegaven should constitute 10 - 20% of this intake.

Method of administration

•   For infusion via central or peripheral vein.
•   Containers should be shaken before use.
•   When Omegaven is to be administered with other infusion solutions (eg amino acid solutions, cabohydrate solutions) via a common infusion line (by-pass, y-tube), the compatibility of the solutions/emulsions used must be ensured.

Duration of administration

The duration of administration should not exceed 4 weeks.